The Application of an Enamel Matrix Protein Derivative (Emdogain®) in Regenerative Periodontal Therapy: A Review

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The application of an enamel matrix protein derivative (Emdogain) in regenerative periodontal therapy: a review.

Regenerative periodontal therapy aims at reconstitution of the lost periodontal structures such as new formation of root cementum, periodontal ligament and alveolar bone. Findings from basic research indicate that enamel matrix protein derivative (EMD) has a key role in periodontal wound healing. Histological results from animal and human studies have shown that treatment with EMD promotes peri...

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Periodontal regenerative potential using enamel matrix proteins (EMDOGAIN®)

O ne way to attempt periodontal regeneration is to mimic the biologic processes involved in nascent tooth development, especially the development of the root and the supporting tissues. The EMDOGAIN® (BIORA AB, Malmö, Sweden) concept is based on the discovery that enamel matrix proteins are not only involved in enamel formation but also play a key role in the formation of acellular cementum [1,...

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Emdogain in regenerative periodontal therapy. A review of the literature.

The goal of regenerative periodontal therapy is the reconstitution of the lost periodontal structures (i.e. the new formation of root cementum, periodontal ligament and alveolar bone). Results from basic research have pointed to the important role of the enamel matrix protein derivative (EMD) in the periodontal wound healing. Histological results from animal and human studies have shown that tr...

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Enamel matrix derivative (EMDOGAIN) in the treatment of intrabony periodontal defects.

The aim of the present clinical trial was to compare the long-term effect of EMDOGAIN treatment as an adjunct to modified widman flap (MWF) surgery with the effect of MWF and placebo treatment. The investigation was a placebo-controlled, randomized multicenter trial involving 33 subjects with 34 paired test and control sites. The protocol required 2 interproximal sites, appropriately separated,...

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Enamel matrix derivative (Emdogain) for periodontal tissue regeneration in intrabony defects.

BACKGROUND Periodontitis is a chronic infective disease of the gums caused by bacteria present in dental plaque. This condition induces the breakdown of the tooth supporting apparatus until teeth are lost. Surgery may be indicated to arrest disease progression and regenerate lost tissues. Several surgical techniques have been developed to regenerate periodontal tissues including guided tissue r...

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ژورنال

عنوان ژورنال: Medical Principles and Practice

سال: 2007

ISSN: 1011-7571,1423-0151

DOI: 10.1159/000100386